Liver sometimes can’t fix itself, even after you quit alcohol: Scientists explain why heavy drinking stops the liver from healing

New research reveals why alcohol-damaged livers cannot heal themselves. Liver cells get stuck in a repair limbo, unable to fully regenerate. RNA splicing problems and a missing protein, ESRP2, prevent tissue regrowth. Inflammation further suppresses ESRP2. These findings could lead to new treatments for alcohol-related liver disease, providing alternatives to transplants.

Liver sometimes can’t fix itself, even after you quit alcohol: Scientists explain why heavy drinking stops the liver from healing
New research reveals why alcohol-damaged livers cannot heal themselves. Liver cells get stuck in a repair limbo, unable to fully regenerate. RNA splicing problems and a missing protein, ESRP2, prevent tissue regrowth. Inflammation further suppresses ESRP2. These findings could lead to new treatments for alcohol-related liver disease, providing alternatives to transplants.